Browse all practice questions for the Certified Addictions Registered Nurse (CARN) Advanced Practice (AP) Practice Test. Search by topic, open any question and review its full explanation, then test yourself in the practice quiz.

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  • Which neurotransmitter is released in reward pathways and linked to reinforcement in the brain?
  • How many criteria must be met to qualify as severe SUD?
  • Which stage defined as having recently changed behavior and intending to maintain that change is the:
  • Which DSM-5 criterion refers to craving or spending a lot of time using?
  • ALDH5A1 is best described as which type of biomolecule?
  • Which option identifies the substance that is NOT a stimulant category?
  • Which option correctly identifies the Yale Food Addiction Scale (YFAS)?
  • Which of the following is a sign of benzodiazepine intoxication?
  • Which medication is used as an opioid receptor antagonist for relapse prevention in opioid dependence?
  • Which drug class is used to treat agitation, muscle rigidity, seizures, and hypertension associated with MDMA overdose?
  • What is Cocaine's mechanism of action?
  • Chronic cocaine use can result in which of the following nasal findings?
  • Amphetamines increase the activity of which neurotransmitters?
  • Personalization in counseling refers to which concept?
  • Which DSM-5 criterion refers to neglecting major life roles and social/interpersonal problems due to substance use?
  • Acamprosate should not be given in which impairment?
  • In TTFC assessment, severe tobacco use is defined as tobacco use within how many minutes after waking?
  • What is the Yale Food Addiction Scale (YFAS) primarily designed to identify?
  • How many DSM-5 criteria indicate a mild substance use disorder?
  • The Hooked on Nicotine Checklist (HONC) is a tool used to assess risk of what?
  • Which of the following is a symptom of systemic anabolic steroid use in women?
  • Pharmacological treatment increases quit rates by approximately how many times?
  • For an amphetamine overdose, what is the recommended treatment if the patient presents within one hour?
  • What gene is commonly involved in non-responsive patients on MOUD?
  • What is the brand name for varenicline?
  • Which of the following is the generic name for the opioid overdose reversal agent?
  • Which of the following is NOT listed as a tobacco withdrawal symptom?
  • Which statement best describes a typical YFAS administration time? (Most true statement)
  • How many items are on the SOCRATES self-report test?
  • What is the pharmacologic action of disulfiram when alcohol is consumed?
  • GABA is excitatory or inhibitory?
  • Which product should be avoided while taking disulfiram due to potential reaction with alcohol?
  • Methamphetamine is a blank form of dopamine.
  • What does GABBA do?
  • Which reflection response is best when a patient expresses concern about others judging them for smoking?
  • For an amphetamine overdose within one hour, which agent is advised?
  • According to the 2018 National Survey on Drug Use and Health, the rate of heavy drinking is approximately:
  • Bupropion (Wellbutrin) mimics the effects of nicotine by increasing which neurotransmitters?
  • Which statement identifies a NOT typical symptom of methamphetamine withdrawal?
  • What is the recommended maximum number of drinks per day for adults?
  • To be classified as having a substance use disorder per DSM-5, at least how many criteria must be met?
  • Which component of OARS involves restating what the client has said to ensure understanding?
  • What is the brand name for acamprosate?
  • Which medication blocks opioid receptors to reduce the pleasant effects of alcohol?
  • What is the brand name for bupropion?
  • To be eligible for naltrexone after opioid use, how long must a person be abstinent from all opioids, including buprenorphine?
  • Drowsiness is prevalent at what blood alcohol level?
  • Phencyclidine is the full name of which drug?
  • Gamma glutamyl transferase (GGT) is best described as which of the following?
  • The Situational Confidence Questionnaire (SCQ) measures adherence to treatment in patients with addiction.
  • What does the biopsychosocial model describe?
  • The Inventory of Drinking Situations is used to identify emotional, cognitive, and social factors that may precipitate drinking.
  • Which TTFC timeframe is associated with severe tobacco use?
  • Which statement about the Inventory of Drinking Situations is true?
  • Which statement about nicotine prevalence is true?
  • Which of the following is a DSM-5 criterion for a substance use disorder?
  • Amphetamine toxicity causes BLANK pupils.
  • Which drug is associated with euphoria or rage, reddish skin, dilated pupils, nystagmus, and excitation?
  • The Coping Response Inventory assesses what?
  • GABRA6 is best described as which type of molecule?
  • For starting Naltrexone in AUD/OUD, abstinence from alcohol must be maintained for how long prior to initiation?
  • Who typically completes the Yale Food Addiction Scale?
  • Which of the following best describes the YFAS content?
  • Which of the following is a component of the OARS framework used in motivational interviewing?
  • Analeptics are best described as drugs that do what?
  • Which medication is considered the most effective for treating nicotine dependence?
  • Which stage is defined by considering change within the next six months?
  • Can patients smoke while using nicotine replacement therapy (NRT)?
  • Above which blood alcohol level can be fatal?
  • Chronic cocaine use is associated with vasculitis-like syndromes similar to Raynaud's phenomenon. This statement is:
  • At what blood alcohol level do signs of intoxication start to become obvious?
  • The Situational Confidence Questionnaire consists of how many self-reported questions?
  • Which statement best captures the core spirit of Motivational Interviewing?
  • In relation to alcohol withdrawal, which mechanism is listed for quetiapine in the material?
  • Which statement by Steve is the best indicator of his readiness to change?
  • Which trio represents the three stimulant drug categories?
  • What is the first-line treatment for acute psychosis?
  • In this stage, people have recently changed their behavior (defined as within the last 6 months) and intend to keep moving forward with that behavior change.
  • What is the lifetime prevalence of nicotine use?
  • Quetiapine (Seroquel) is associated with affecting which neurotransmitter systems?
  • Which term describes a molecule that increases a neurotransmitter's action?
  • In Motivational Interviewing, which element is central to evoking change?
  • Which assessment measures a patient's motivation to change drinking behavior?
  • Compared with nicotine replacement therapy or bupropion, varenicline has what quit rates?
  • Glutamate is excitatory or inhibitory?
  • Varenicline is best described as which of the following?
  • When used for alcohol use disorders, topiramate is documented to do which of the following?
  • Which term describes a molecule that blocks receptor activation?
  • The hallmark clinical feature of drug-induced thrombotic microangiopathy (DITMA) is which of the following?
  • What is the maximum first dose allowed by law in a methadone maintenance program?
  • In the CAGE questionnaire, what does the letter 'G' stand for?
  • Which statement is true about disulfiram and alcohol interactions?
  • Delirium tremens usually begins how many days after surgery?
  • Which item is NOT part of the OARS framework?
  • Acamprosate is used to maintain abstinence and reduce post-acute withdrawal symptoms. Which choice best reflects this statement?
  • Buprenorphine is used in office-based treatment for which condition?
  • LSD effects have the following onset, peak, and duration: onset 30–60 minutes; peak 2–4 hours; duration 8–12 hours. Which option matches this description?
  • What is the primary goal of cognitive-behavioral therapy (CBT)?
  • Which of the following are common symptoms of alcohol withdrawal?
  • Disulfiram should be avoided with which everyday product due to potential alcohol content?
  • What does glutamate do?
  • Disulfiram is a daily oral medication to sustain abstinence from alcohol; this is considered what type of therapy?
  • Benzodiazepines bind at what receptor?
  • Which of the following is a symptom of opioid withdrawal related to pupil size?
  • Stage of change in which people are unwilling to change their behavior?
  • Acamprosate is indicated for which purpose?
  • LSD is a hallucinogen that elevates activity of which neurotransmitter system?
  • Endogenous opioids have what effect on pain and mood?
  • Which medication is a non-nicotine pharmacotherapy for nicotine dependence that increases dopamine and norepinephrine?
  • In research on Motivational Interviewing with diverse communities, which statement best reflects effectiveness?
  • The peak effects of LSD typically occur within how many hours after onset?
  • What is the full name of PCP?
  • In motivational interviewing, which technique involves reflecting the client's meaning and emotions back to them?
  • In the Precontemplation stage of behavior change, how is the individual typically described?
  • Which statement correctly describes the relationship between glutamate and GABA as described?
  • To start Naltrexone for AUD or OUD, abstinence from alcohol must be maintained for how long?
  • According to the DSM-5 criteria, how many criteria indicate a mild substance use disorder?
  • Which of the following is a tobacco withdrawal symptom?
  • Which medication is used to treat serotonin syndrome?
  • What causes hangover-like symptoms when drinking while taking disulfiram?
  • Which is a common cardiovascular symptom of opioid withdrawal?
  • Barbiturates are best described as what?
  • The half-life of nicotine is approximately how many hours?
  • What buprenorphine dose was the patient advanced to in the described case?
  • Naltrexone is used to treat AUD by which mechanism?
  • Which stimulus causes the greatest peak dopamine release in the brain among the following options?
  • Which statement best reflects proficiency in Motivational Interviewing practice?
  • Which medication is a partial opioid agonist used in maintenance therapy?
  • What is the typical duration of LSD effects?
  • In a case of opioid use disorder treated with buprenorphine, the most appropriate next step when there is concurrent benzodiazepine use and alcohol intake is to:
  • Which substance is used to treat serotonin syndrome?
  • Amphetamines exert their effect by blocking the reuptake of which two neurotransmitters?
  • What is the generic name for the medication marketed as Vivitrol?
  • Which instrument is described as assessing coping skills for relapse prevention?
  • Daily naltrexone dosing for AUD is which?
  • What is the name brand of Bupropion?
  • In stimulant-induced psychosis, which class of medication is considered first-line treatment?
  • Which statement accurately reflects the effect of pharmacological treatment on smoking cessation according to the material?
  • What is the lifetime risk of alcohol dependence?
  • Methamphetamine is a blank form of dopamine.
  • What is the treatment for mild to moderate amphetamine overdose?
  • How long after the last drink can disulfiram be started?
  • What is the action of benzodiazepines in alcohol withdrawal management?
  • What is the neuropharmacological pathway through which topiramate exerts its effects in alcohol use disorder?
  • The amygdala plays an important role in which function?
  • Which counseling point is essential for disulfiram use?
  • Disulfiram blocks which enzyme in the brain?
  • Cannabis withdrawal symptoms listed include which of the following?
  • Which medication is described as helping abstinence from alcohol by dampening glutamate activity?
  • In the CAGE questionnaire, what does the letter 'C' stand for?
  • Which statement best describes what the YFAS aims to identify?
  • True or False: Heavy and binge drinking rates have shown a significant increase in recent trends.
  • Which medication is used for alcohol aversion therapy and is known by brand Antabuse?
  • Which neurotransmitter system is most directly linked to inhibitory control in the CNS, commonly targeted by sedatives including benzodiazepines?
  • What is the first-line treatment for delirium tremens?
  • In the Contemplation stage, individuals are:
  • Benzo's activate the BLANK receptor causing sedation.
  • How long does it take to complete the Yale Food Addiction Scale (YFAS)?
  • In the management of delirium tremens, which class of medications is commonly used?
  • In Nicorette or generic gum, what factor determines the milligram dosing?
  • Fentanyl is classified as which type of opioid?
  • What does increased endogenous opioids do?
  • Which neurotransmitter is described as increasing pleasure or reinforcement?
  • How many days before cessation should patients start bupropion?
  • Which medication blocks opioid receptors to reduce the rewarding effects of alcohol?
  • Which medication is associated with the brand Wellbutrin?
  • Alprazolam (Xanax) is classified as which type of medication?
  • Coma can occur at what blood alcohol level?
  • Stage of change in which people are considering changing behavior in the next 6 months?
  • Binge drinking - amount for men and women.
  • Bupropion (Wellbutrin) increases which neurotransmitters?
  • Nervousness, tremor, agitation, and hypotension may occur from abrupt discontinuation of BLANK.
  • Amnesia, severe dysarthria, and sometimes hypothermia are seen at which level?
  • What is the first-line treatment for symptoms of acute stimulant-induced psychosis?
  • Is concomitant use of varenicline with nicotine replacement therapy recommended?
  • Bupropion is commonly used to treat which condition?
  • Heavy (At risk) Drinking - amount for men and women.
  • Which of the following represents the standard size of one drink?
  • The 5th stage of change focuses on preventing relapse and consolidating gains. Which stage is described?
  • The Inventory of Drinking Situations is a 100-item self-report instrument.
  • Methadone is an opioid: antagonist or agonist?
  • What is the typical daily dose range for disulfiram?
  • In TTFC assessment, moderate tobacco use is defined as smoking within which minutes after waking?
  • Bupropion is commonly marketed under which brand name?
  • YFAS is named after which institution?
  • What is a partial agonist?
  • PCP acts primarily as an antagonist at which receptor?
  • What is the typical daily dose range for bupropion when used for tobacco cessation?
  • Which statement about the YFAS is accurate?
  • What is the most widely used stimulant?
  • Is the YFAS self-reported?
  • Which brain structure is responsible for the reinforcing nature of opioid use?
  • Varenicline reduces the effects of nicotine by blocking receptors.
  • Which of the following statements is true regarding opiates and opioids?
  • PCP is best described as which type of drug?
  • In the CAGE questionnaire, what does the letter 'A' stand for?
  • What is the action of varenicline in smoking cessation?
  • Acamprosate (Campral) helps abstinence from alcohol by what mechanism?
  • Which of the following is a sign of opioid withdrawal?
  • Naltrexone is a mu opioid receptor BLANK.
  • What percentage of adults have had exposure to alcohol?
  • Nicotine's effects in the central nervous system include which of the following?
  • Acamprosate (Campral) does what to GABA and glutamate levels?
  • The YFAS focuses on markers of substance dependence in relation to the consumption of what type of foods?
  • What does dopamine do?
  • What is the primary objective of the Maintenance stage in the stage-of-change model described?
  • Which statement best describes the Hooked on Nicotine Checklist (HONC) in clinical use?
  • What is the generic name of Narcan?
  • Which of the following is a contraindication to bupropion?
  • Acamprosate (Campral) dosing is which of the following?
  • Which medication is a full opioid agonist used in maintenance therapy?
  • Varenicline is marketed under which brand name?
  • What type of assessment is the YFAS?
  • Which statement best describes a full agonist's effect at a receptor?
  • Which of the following are among the most common symptoms of methamphetamine withdrawal?
  • What is the primary purpose of the CAGE questionnaire?
  • Which statement best describes the YFAS purpose?
  • Which symptoms may occur when alcohol is consumed after taking disulfiram (Antabuse)?
  • Disulfiram (Antabuse) acts by...
  • Delirium tremens is typically treated with which medication?
  • gamma-Glutamyl transferase (GGT) serves as a biomarker for which clinical parameter?
  • Disulfiram works as a pharmacologic intervention primarily by causing a severe reaction when alcohol is consumed; this describes which concept?
  • What is the approximate prevalence of inhalant use in adolescents?
  • Which statement correctly differentiates opioids from opiates?
  • What gene is involved in alcohol flushing?
  • What is an antagonist?
  • Delirium tremens typically begins within how many hours after the last drink?
  • Flumazenil is used to reverse which category of substances?
  • Which of the following is a documented effect of topiramate in alcohol use disorder treatment?
  • How quickly can tolerance develop to benzodiazepines with continued use?
  • DITMA is defined as which of the following?
  • According to the material, a severe substance use disorder is indicated by more than how many criteria?
  • Which type of data does the YFAS primarily rely on?
  • PCP acts on which receptor type?
  • Which term describes a drug that produces a weaker response than a full agonist?
  • What is the 12-month prevalence rate of nicotine use?
  • What is the brand name associated with baclofen?
  • Approximately how long does it typically take to complete the YFAS?
  • Baclofen (Lioresal) is best classified as what type of medication?
  • Which neurotransmitter is associated with speeding neural activity?
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